This article seeks to establish the biblical and theological foundations for teamwork and team leadership for ministry practice. In order to understand and evaluate the applicability of a ministry team approach, selected models of team leadership in both the Old and New Testaments are explored. Some biblical concepts including love, unity, and the image of the body, together with concepts such as co-laborer, plurality of leadership, shared leadership, and servant leadership, are also explored. The models and concepts reviewed show key elements and spiritual principles for leading ministry teams. Scriptures clearly depict teamwork through the practice of loving each other and living in the unity of the Spirit to the building up of the body of Christ. Therefore, a ministry team approach structured upon biblical and theological foundations should help the church to work together harmoniously and corporately as intended by Jesus Christ, the founder and head of the Christian church.